Peripheral vascular disease

3 g daily in 2–3 divided doses, maximum 4 g daily

Molecular weight :810.7

%Protein binding :High

%Excreted unchanged in urine : No data

Volume of distribution (L/kg) :No data

half-life – normal/ESRD (hrs) :24

30–50 Dose as in normal renal function10–30 Dose as in normal renal function

<10 : Dose as in normal renal function

CAPD :Unknown dialysability. Dose as in normal renal function

HD :Unknown dialysability. Dose as in normal renal function

HDF/high flux :Unknown dialysability. Dose as in normal renal function

CAV/VVHD :Unknown dialysability. Dose as in normal renal function

Potentially hazardous interactions with other drugs

None known

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Oral

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Slowly hydrolysed to nicotinic acid inositol nicotinate.